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Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania

Aneuploidy causes system-wide disruptions in the stochiometric balances of transcripts, proteins, and metabolites, often resulting in detrimental effects for the organism. The protozoan parasite Leishmania has an unusually high tolerance for aneuploidy, but the molecular and functional consequences...

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Detalles Bibliográficos
Autores principales: Cuypers, Bart, Meysman, Pieter, Erb, Ionas, Bittremieux, Wout, Valkenborg, Dirk, Baggerman, Geert, Mertens, Inge, Sundar, Shyam, Khanal, Basudha, Notredame, Cedric, Dujardin, Jean-Claude, Domagalska, Malgorzata A., Laukens, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534393/
https://www.ncbi.nlm.nih.gov/pubmed/36149920
http://dx.doi.org/10.1371/journal.ppat.1010848