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Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania
Aneuploidy causes system-wide disruptions in the stochiometric balances of transcripts, proteins, and metabolites, often resulting in detrimental effects for the organism. The protozoan parasite Leishmania has an unusually high tolerance for aneuploidy, but the molecular and functional consequences...
Autores principales: | Cuypers, Bart, Meysman, Pieter, Erb, Ionas, Bittremieux, Wout, Valkenborg, Dirk, Baggerman, Geert, Mertens, Inge, Sundar, Shyam, Khanal, Basudha, Notredame, Cedric, Dujardin, Jean-Claude, Domagalska, Malgorzata A., Laukens, Kris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534393/ https://www.ncbi.nlm.nih.gov/pubmed/36149920 http://dx.doi.org/10.1371/journal.ppat.1010848 |
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