Functional inference of gene regulation using single-cell multi-omics

Cells require coordinated control over gene expression when responding to environmental stimuli. Here we apply scATAC-seq and single-cell RNA sequencing (scRNA-seq) in resting and stimulated human blood cells. Collectively, we generate ∼91,000 single-cell profiles, allowing us to probe the cis-regul...

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Detalles Bibliográficos
Autores principales: Kartha, Vinay K., Duarte, Fabiana M., Hu, Yan, Ma, Sai, Chew, Jennifer G., Lareau, Caleb A., Earl, Andrew, Burkett, Zach D., Kohlway, Andrew S., Lebofsky, Ronald, Buenrostro, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534481/
https://www.ncbi.nlm.nih.gov/pubmed/36204155
http://dx.doi.org/10.1016/j.xgen.2022.100166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534481/
https://www.ncbi.nlm.nih.gov/pubmed/36204155
http://dx.doi.org/10.1016/j.xgen.2022.100166

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