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A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression

Embryogenesis is supported by dynamic loops of cellular interactions. Here, we create a partial mouse embryo model to elucidate the principles of epiblast (Epi) and extra-embryonic endoderm co-development (XEn). We trigger naive mouse embryonic stem cells to form a blastocyst-stage niche of Epi-like...

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Detalles Bibliográficos
Autores principales: Vrij, Erik J., Scholte op Reimer, Yvonne S., Fuentes, Laury Roa, Guerreiro, Isabel Misteli, Holzmann, Viktoria, Aldeguer, Javier Frias, Sestini, Giovanni, Koo, Bon-Kyoung, Kind, Jop, van Blitterswijk, Clemens A., Rivron, Nicolas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534490/
https://www.ncbi.nlm.nih.gov/pubmed/35993866
http://dx.doi.org/10.1242/dev.192310