POU2AF2/C11orf53 functions as a coactivator of POU2F3 by maintaining chromatin accessibility and enhancer activity

Small cell lung cancer (SCLC), accounting for around 13% of all lung cancers, often results in rapid tumor growth, early metastasis, and acquired therapeutic resistance. The POU class 2 homeobox 3 (POU2F3) is a master regulator of tuft cell identity and defines the SCLC-P subtype that lacks the neur...

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Detalles Bibliográficos
Autores principales: Szczepanski, Aileen Patricia, Tsuboyama, Natsumi, Watanabe, Jun, Hashizume, Rintaro, Zhao, Zibo, Wang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534498/
https://www.ncbi.nlm.nih.gov/pubmed/36197978
http://dx.doi.org/10.1126/sciadv.abq2403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534498/
https://www.ncbi.nlm.nih.gov/pubmed/36197978
http://dx.doi.org/10.1126/sciadv.abq2403

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