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Suppression of estrogen receptor beta classical genomic activity enhances systemic and adipose-specific response to chronic beta-3 adrenergic receptor (β3AR) stimulation

White adipose tissue (WAT) dysfunction independently predicts cardiometabolic disease, yet there is a lack of effective adipocyte-targeting therapeutics. B3AR agonists enhance adipocyte mitochondrial function and hold potential in this regard. Based on enhanced sensitivity to B3AR-mediated browning...

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Detalles Bibliográficos
Autores principales: Queathem, Eric D., Fitzgerald, Maggie, Welly, Rebecca, Rowles, Candace C., Schaller, Kylie, Bukhary, Shahad, Baines, Christopher P., Rector, R. Scott, Padilla, Jaume, Manrique-Acevedo, Camila, Lubahn, Dennis B., Vieira-Potter, Victoria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534559/
https://www.ncbi.nlm.nih.gov/pubmed/36213237
http://dx.doi.org/10.3389/fphys.2022.920675