Activation of PPARγ Protects Obese Mice from Acute Lung Injury by Inhibiting Endoplasmic Reticulum Stress and Promoting Mitochondrial Biogenesis

OBJECTIVE: Obesity-induced endoplasmic reticulum (ER) stress plays a role in increased susceptibility to acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). The activation of peroxisome proliferator-activated receptor-γ (PPARγ) is associated with lung protection and is effective in a...

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Detalles Bibliográficos
Autores principales: Tang, Yin, Wei, Ke, Liu, Ling, Ma, Jingyue, Wu, Siqi, Tang, Wenjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534695/
https://www.ncbi.nlm.nih.gov/pubmed/36213491
http://dx.doi.org/10.1155/2022/7888937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534695/
https://www.ncbi.nlm.nih.gov/pubmed/36213491
http://dx.doi.org/10.1155/2022/7888937

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