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Activation of PPARγ Protects Obese Mice from Acute Lung Injury by Inhibiting Endoplasmic Reticulum Stress and Promoting Mitochondrial Biogenesis
OBJECTIVE: Obesity-induced endoplasmic reticulum (ER) stress plays a role in increased susceptibility to acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). The activation of peroxisome proliferator-activated receptor-γ (PPARγ) is associated with lung protection and is effective in a...
Autores principales: | Tang, Yin, Wei, Ke, Liu, Ling, Ma, Jingyue, Wu, Siqi, Tang, Wenjing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534695/ https://www.ncbi.nlm.nih.gov/pubmed/36213491 http://dx.doi.org/10.1155/2022/7888937 |
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