Cargando…

T Lymphocyte-Derived Exosomes Transport MEK1/2 and ERK1/2 and Induce NOX4-Dependent Oxidative Stress in Cardiac Microvascular Endothelial Cells

BACKGROUND: Activation of endothelial cells by inflammatory mediators secreted by CD4(+) T lymphocytes plays a key role in the inflammatory response. Exosomes represent a specific class of signaling cues transporting a mixture of proteins, nucleic acids, and other biomolecules. So far, the impact of...

Descripción completa

Detalles Bibliográficos
Autores principales: Rolski, Filip, Czepiel, Marcin, Tkacz, Karolina, Fryt, Katarzyna, Siedlar, Maciej, Kania, Gabriela, Błyszczuk, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534701/
https://www.ncbi.nlm.nih.gov/pubmed/36211827
http://dx.doi.org/10.1155/2022/2457687