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T Lymphocyte-Derived Exosomes Transport MEK1/2 and ERK1/2 and Induce NOX4-Dependent Oxidative Stress in Cardiac Microvascular Endothelial Cells

BACKGROUND: Activation of endothelial cells by inflammatory mediators secreted by CD4(+) T lymphocytes plays a key role in the inflammatory response. Exosomes represent a specific class of signaling cues transporting a mixture of proteins, nucleic acids, and other biomolecules. So far, the impact of...

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Detalles Bibliográficos
Autores principales:	Rolski, Filip, Czepiel, Marcin, Tkacz, Karolina, Fryt, Katarzyna, Siedlar, Maciej, Kania, Gabriela, Błyszczuk, Przemysław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534701/ https://www.ncbi.nlm.nih.gov/pubmed/36211827 http://dx.doi.org/10.1155/2022/2457687

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