Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population

Physiologically based pharmacokinetic (PBPK) modeling can be an attractive tool to increase the evidence base of pediatric drug dosing recommendations by making optimal use of existing pharmacokinetic (PK) data. A pragmatic approach of combining available compound models with a virtual pediatric phy...

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Detalles Bibliográficos
Autores principales: Freriksen, Jolien J. M., van der Heijden, Joyce E. M., de Hoop-Sommen, Marika A., Greupink, Rick, de Wildt, Saskia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Current Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534738/
https://www.ncbi.nlm.nih.gov/pubmed/36201128
http://dx.doi.org/10.1007/s40272-022-00535-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534738/
https://www.ncbi.nlm.nih.gov/pubmed/36201128
http://dx.doi.org/10.1007/s40272-022-00535-w

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