Cargando…

Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population

Physiologically based pharmacokinetic (PBPK) modeling can be an attractive tool to increase the evidence base of pediatric drug dosing recommendations by making optimal use of existing pharmacokinetic (PK) data. A pragmatic approach of combining available compound models with a virtual pediatric phy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Freriksen, Jolien J. M., van der Heijden, Joyce E. M., de Hoop-Sommen, Marika A., Greupink, Rick, de Wildt, Saskia N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Current Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534738/ https://www.ncbi.nlm.nih.gov/pubmed/36201128 http://dx.doi.org/10.1007/s40272-022-00535-w

Ejemplares similares

Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care
por: van der Heijden, Joyce E. M., et al.
Publicado: (2022)

Lamivudine and Emtricitabine Dosing Proposal for Children with HIV and Chronic Kidney Disease, Supported by Physiologically Based Pharmacokinetic Modelling
por: Jacobs, Tom G., et al.
Publicado: (2023)

Requirements to Establishing Confidence in Physiologically Based Pharmacokinetic (PBPK) Models and Overcoming Some of the Challenges to Meeting Them
por: Peters, Sheila Annie, et al.
Publicado: (2019)

Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically‐Based Pharmacokinetic Modeling
por: Freriksen, Jolien J.M., et al.
Publicado: (2020)

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling
por: Schalkwijk, Stein, et al.
Publicado: (2017)

The Patient’s Voice in Pharmacovigilance: Pragmatic Approaches to Building a Patient-Centric Drug Safety Organization
por: Smith, Meredith Y., et al.
Publicado: (2016)

External Validation of Model-Based Dosing Guidelines for Vancomycin, Gentamicin, and Tobramycin in Critically Ill Neonates and Children: A Pragmatic Two-Center Study
por: Hartman, Stan J. F., et al.
Publicado: (2020)

‘Highest risk–highest benefit’ strategy: a pragmatic, cost-effective approach to targeting use of PCSK9 inhibitor therapies
por: Annemans, Lieven, et al.
Publicado: (2018)

Clinical Pharmacokinetics and Impact of Hematocrit on Monitoring and Dosing of Tacrolimus Early After Heart and Lung Transplantation
por: Sikma, Maaike A., et al.
Publicado: (2019)

Pharmacokinetics and Generic Drug Switching: A Regulator’s View
por: Glerum, Pieter J., et al.
Publicado: (2020)

Off‐Label, but on‐Evidence? A Review of the Level of Evidence for Pediatric Pharmacotherapy
por: van der Zanden, Tjitske M., et al.
Publicado: (2022)

Tinzaparin Sodium Pharmacokinetics in Patients with Chronic Kidney Disease: Practical Implications
por: Helfer, Hélène, et al.
Publicado: (2019)

Mpox and Monkeypox Virus: Special Considerations for Athletes in Contact Sports
por: Smoliga, James M.
Publicado: (2023)

Combining Isotopic Tracer Techniques to Increase Efficiency of Clinical Pharmacokinetic Trials in Oncology
por: Roosendaal, Jeroen, et al.
Publicado: (2020)

Specialization in acute care surgery in low-income and middle-income countries
por: Yi, Sojung, et al.
Publicado: (2017)

Limitations of the SCORE-guided European guidelines on cardiovascular disease prevention
por: Mortensen, Martin Bødtker, et al.
Publicado: (2017)

Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties
por: Smit, Cornelis, et al.
Publicado: (2020)

Azithromycin in COVID-19 Patients: Pharmacological Mechanism, Clinical Evidence and Prescribing Guidelines
por: Sultana, Janet, et al.
Publicado: (2020)

Biologic Treatment Algorithms for Moderate-to-Severe Psoriasis with Comorbid Conditions and Special Populations: A Review
por: Thatiparthi, Akshitha, et al.
Publicado: (2021)

Omadacycline Oral Dosing and Pharmacokinetics in Community-Acquired Bacterial Pneumonia and Acute Bacterial Skin and Skin Structure Infection
por: Leviton, Ira M., et al.
Publicado: (2022)

Clinical Implications of the 2013 ESH/ESC Hypertension Guidelines: Targets, Choice of Therapy, and Blood Pressure Monitoring
por: Kjeldsen, Sverre E., et al.
Publicado: (2014)

NSTE-ACS ESC Guidelines Recommend Prasugrel as the Preferred P2Y12 Inhibitor: A Contrarian View
por: Angoulvant, Denis, et al.
Publicado: (2021)

Are the Current Guidelines on Caffeine Use in Sport Optimal for Everyone? Inter-individual Variation in Caffeine Ergogenicity, and a Move Towards Personalised Sports Nutrition
por: Pickering, Craig, et al.
Publicado: (2017)

Application of Physiologically Based Pharmacokinetic (PBPK) Modeling to Support Dose Selection: Report of an FDA Public Workshop on PBPK
por: Wagner, C, et al.
Publicado: (2015)

Network Physiology of Exercise: Beyond Molecular and Omics Perspectives
por: Balagué, Natàlia, et al.
Publicado: (2022)

Recent Improvements in Marathon Run Times Are Likely Technological, Not Physiological
por: Muniz-Pardos, Borja, et al.
Publicado: (2021)

‘Aerobic’ and ‘Anaerobic’ terms used in exercise physiology: a critical terminology reflection
por: Chamari, Karim, et al.
Publicado: (2015)

Physiologically Based Pharmacokinetic (PBPK) Modeling of Metabolic Pathways of Bromochloromethane in Rats
por: Cuello, W. S., et al.
Publicado: (2012)

Current Approaches and Techniques in Physiologically Based Pharmacokinetic (PBPK) Modelling of Nanomaterials
por: Utembe, Wells, et al.
Publicado: (2020)

Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development
por: Shaik, Abdul Naveed, et al.
Publicado: (2019)

Rheological and Physiological Consequences of Conversion of the Maternal Spiral Arteries for Uteroplacental Blood Flow during Human Pregnancy
por: Burton, G.J., et al.
Publicado: (2009)

Physiologically-Based Pharmacokinetic (PBPK) Modeling Providing Insights into Fentanyl Pharmacokinetics in Adults and Pediatric Patients
por: Kovar, Lukas, et al.
Publicado: (2020)

Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations
por: Ke, Alice Ban, et al.
Publicado: (2018)

Preparedness of pharmacists to respond to the emergency of the COVID-19 pandemic in Brazil: a comprehensive overview
por: Parreiras Martins, Maria Auxiliadora, et al.
Publicado: (2020)

Medical Information Delivering Improved Customer Experience: A Guide
por: Guillot, Pete, et al.
Publicado: (2023)

Should Heartbeats/Training Session Be Considered When Comparing the Cardiovascular Benefits of High-Intensity Interval Aerobic and Moderate-Intensity Continuous Training? A Critical Appraisal
por: Rodrigues, Jhennyfer Aline Lima, et al.
Publicado: (2020)

Development of a Human Physiologically Based Pharmacokinetic (PBPK) Toolkit for Environmental Pollutants
por: Ruiz, Patricia, et al.
Publicado: (2011)

Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse
por: Chiu, Weihsueh A., et al.
Publicado: (2014)

Physiologically-Based Pharmacokinetic (PBPK) Modeling of Buprenorphine in Adults, Children and Preterm Neonates
por: Kovar, Lukas, et al.
Publicado: (2020)

Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Brain Levels of Drug in Rat
por: Sánchez-Dengra, Bárbara, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ie8cd9m5s5u5ja9amvm2jljled