Hetero-pentamerization determines mobility and conductance of Glycine receptor α3 splice variants

Glycine receptors (GlyRs) are ligand-gated pentameric chloride channels in the central nervous system. GlyR-α3 is a possible target for chronic pain treatment and temporal lobe epilepsy. Alternative splicing into K or L variants determines the subcellular fate and function of GlyR-α3, yet it remains...

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Detalles Bibliográficos
Autores principales: Lemmens, Veerle, Thevelein, Bart, Vella, Yana, Kankowski, Svenja, Leonhard, Julia, Mizuno, Hideaki, Rocha, Susana, Brône, Bert, Meier, Jochen C., Hendrix, Jelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534812/
https://www.ncbi.nlm.nih.gov/pubmed/36197517
http://dx.doi.org/10.1007/s00018-022-04506-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534812/
https://www.ncbi.nlm.nih.gov/pubmed/36197517
http://dx.doi.org/10.1007/s00018-022-04506-9

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