Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome

Hypoplastic left heart syndrome (HLHS) is characterized by underdevelopment of left sided structures including the ventricle, valves, and aorta. Prevailing paradigm suggests that HLHS is a multigenic disease of co-occurring phenotypes. Here, we report that zebrafish lacking two orthologs of the RNA...

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Detalles Bibliográficos
Autores principales: Huang, Mengmeng, Akerberg, Alexander A., Zhang, Xiaoran, Yoon, Haejin, Joshi, Shakchhi, Hallinan, Celia, Nguyen, Christopher, Pu, William T., Haigis, Marcia C., Burns, C. Geoffrey, Burns, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534849/
https://www.ncbi.nlm.nih.gov/pubmed/36198703
http://dx.doi.org/10.1038/s41467-022-32982-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534849/
https://www.ncbi.nlm.nih.gov/pubmed/36198703
http://dx.doi.org/10.1038/s41467-022-32982-x

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