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Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome
Hypoplastic left heart syndrome (HLHS) is characterized by underdevelopment of left sided structures including the ventricle, valves, and aorta. Prevailing paradigm suggests that HLHS is a multigenic disease of co-occurring phenotypes. Here, we report that zebrafish lacking two orthologs of the RNA...
Autores principales: | Huang, Mengmeng, Akerberg, Alexander A., Zhang, Xiaoran, Yoon, Haejin, Joshi, Shakchhi, Hallinan, Celia, Nguyen, Christopher, Pu, William T., Haigis, Marcia C., Burns, C. Geoffrey, Burns, Caroline E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534849/ https://www.ncbi.nlm.nih.gov/pubmed/36198703 http://dx.doi.org/10.1038/s41467-022-32982-x |
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