Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane

Gram-negative porins are the main entry for small hydrophilic molecules. We studied translocation of structurally related cephalosporins, ceftazidime (CAZ), cefotaxime (CTX) and cefepime (FEP). CAZ is highly active on E. coli producing OmpF (Outer membrane protein F) but less efficient on cells expr...

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Detalles Bibliográficos
Autores principales: Masi, Muriel, Vergalli, Julia, Ghai, Ishan, Barba-Bon, Andrea, Schembri, Thérèse, Nau, Werner M., Lafitte, Daniel, Winterhalter, Mathias, Pagès, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534850/
https://www.ncbi.nlm.nih.gov/pubmed/36198902
http://dx.doi.org/10.1038/s42003-022-04035-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534850/
https://www.ncbi.nlm.nih.gov/pubmed/36198902
http://dx.doi.org/10.1038/s42003-022-04035-y

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