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Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling

Runt-related transcription factor 2 (Runx2), a regulator of osteoblast differentiation, is pathologically involved in vascular calcification; however, the significance of Runx2 in cardiac homeostasis remains unclear. Here, we investigated the roles of Runx2 in cardiac remodeling after myocardial inf...

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Detalles Bibliográficos
Autores principales: Tomimatsu, Masashi, Matsumoto, Kotaro, Ashizuka, Moe, Kumagai, Shohei, Tanaka, Shota, Nakae, Takafumi, Yokota, Kosei, Kominami, Shunsuke, Kajiura, Ryota, Okuzaki, Daisuke, Motooka, Daisuke, Shiraishi, Aki, Abe, Takaya, Matsuda, Hideo, Okada, Yoshiaki, Maeda, Makiko, Seno, Shigeto, Obana, Masanori, Fujio, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534857/
https://www.ncbi.nlm.nih.gov/pubmed/36198906
http://dx.doi.org/10.1038/s41598-022-21202-7