Establishment of a humanized animal model of systemic sclerosis in which T helper-17 cells from patients with systemic sclerosis infiltrate and cause fibrosis in the lungs and skin

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by inflammation, microangiopathy, and progressive fibrosis in the skin and internal organs. To evaluate the pathophysiologic mechanisms and efficacies of potential therapeutics for SSc, a preclinical model recapitulating the dise...

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Detalles Bibliográficos
Autores principales: Park, Min-Jung, Park, Youngjae, Choi, Jeong Won, Baek, Jin-Ah, Jeong, Ha Yeon, Na, Hyun Sik, Moon, Young-Mee, Cho, Mi-La, Park, Sung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534900/
https://www.ncbi.nlm.nih.gov/pubmed/36175484
http://dx.doi.org/10.1038/s12276-022-00860-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534900/
https://www.ncbi.nlm.nih.gov/pubmed/36175484
http://dx.doi.org/10.1038/s12276-022-00860-7

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