Cargando…
Establishment of a humanized animal model of systemic sclerosis in which T helper-17 cells from patients with systemic sclerosis infiltrate and cause fibrosis in the lungs and skin
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by inflammation, microangiopathy, and progressive fibrosis in the skin and internal organs. To evaluate the pathophysiologic mechanisms and efficacies of potential therapeutics for SSc, a preclinical model recapitulating the dise...
Autores principales: | Park, Min-Jung, Park, Youngjae, Choi, Jeong Won, Baek, Jin-Ah, Jeong, Ha Yeon, Na, Hyun Sik, Moon, Young-Mee, Cho, Mi-La, Park, Sung-Hwan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534900/ https://www.ncbi.nlm.nih.gov/pubmed/36175484 http://dx.doi.org/10.1038/s12276-022-00860-7 |
Ejemplares similares
-
IL-1-IL-17 Signaling Axis Contributes to Fibrosis and Inflammation in Two Different Murine Models of Systemic Sclerosis
por: Park, Min-Jung, et al.
Publicado: (2018) -
Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis
por: Kuzumi, Ai, et al.
Publicado: (2021) -
Pregnancy Epigenetic Signature in T Helper 17 and T Regulatory Cells in Multiple Sclerosis
por: Iannello, Andrea, et al.
Publicado: (2019) -
Glymphatic system dysfunction in temporal lobe epilepsy patients with hippocampal sclerosis
por: Lee, Dong Ah, et al.
Publicado: (2022) -
Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression
por: Christensen, Jeppe Romme, et al.
Publicado: (2013)