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Congenital adiponectin deficiency mitigates high-fat-diet-induced obesity in gonadally intact male and female, but not in ovariectomized mice

Epidemiological literature indicates that women are less susceptible to type II diabetes (T2D) than males. The general consensus is that estrogen is protective, whereas its deficiency in post-menopause is associated with adiposity and impaired insulin sensitivity. However, epidemiological data sugge...

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Detalles Bibliográficos
Autores principales: Unger, Christian A., Aladhami, Ahmed K., Hope, Marion C., Pourhoseini, Sahar, Nagarkatti, Mitzi, McGuinness, Owen P., Murphy, E. Angela, Velázquez, Kandy T., Enos, Reilly T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534911/
https://www.ncbi.nlm.nih.gov/pubmed/36198723
http://dx.doi.org/10.1038/s41598-022-21228-x