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Aberrant Cholesterol Metabolism and Wnt/β‐Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth

Frizzled (Fzd) proteins are Wnt receptors and play essential roles in development, homeostasis, and oncogenesis. How Wnt/Fzd signaling is coupled to physiological regulation remains unknown. Cholesterol is reported as a signaling molecule regulating morphogen such as Hedgehog signaling. Despite the...

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Detalles Bibliográficos
Autores principales: Zheng, Shaoqin, Lin, Jiahui, Pang, Zhongqiu, Zhang, Hui, Wang, Yinuo, Ma, Lanjing, Zhang, Haijiao, Zhang, Xi, Chen, Maorong, Zhang, Xinjun, Zhao, Chao, Qi, Jun, Cao, Liu, Wang, Min, He, Xi, Sheng, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534957/
https://www.ncbi.nlm.nih.gov/pubmed/35975457
http://dx.doi.org/10.1002/advs.202200750