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Aberrant Cholesterol Metabolism and Wnt/β‐Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth
Frizzled (Fzd) proteins are Wnt receptors and play essential roles in development, homeostasis, and oncogenesis. How Wnt/Fzd signaling is coupled to physiological regulation remains unknown. Cholesterol is reported as a signaling molecule regulating morphogen such as Hedgehog signaling. Despite the...
Autores principales: | Zheng, Shaoqin, Lin, Jiahui, Pang, Zhongqiu, Zhang, Hui, Wang, Yinuo, Ma, Lanjing, Zhang, Haijiao, Zhang, Xi, Chen, Maorong, Zhang, Xinjun, Zhao, Chao, Qi, Jun, Cao, Liu, Wang, Min, He, Xi, Sheng, Ren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534957/ https://www.ncbi.nlm.nih.gov/pubmed/35975457 http://dx.doi.org/10.1002/advs.202200750 |
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