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Activating SIRT3 in peritoneal mesothelial cells alleviates postsurgical peritoneal adhesion formation by decreasing oxidative stress and inhibiting the NLRP3 inflammasome

Peritoneal adhesions (PAs) are a serious complication of abdominal surgery and negatively affect the quality of life of millions of people worldwide. However, a clear molecular mechanism and a standard therapeutic strategy for PAs have not been established. Here, we developed a standardized method t...

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Detalles Bibliográficos
Autores principales: Shen, Tianli, Wu, Yunhua, Wang, Xingjie, Wang, Zijun, Li, Enmeng, Zhou, Cancan, Yue, Chenyang, Jiang, Zhengdong, Wei, Guangbing, Lian, Jie, Xu, Qinhong, Li, Xuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535009/
https://www.ncbi.nlm.nih.gov/pubmed/36100663
http://dx.doi.org/10.1038/s12276-022-00848-3