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Activating SIRT3 in peritoneal mesothelial cells alleviates postsurgical peritoneal adhesion formation by decreasing oxidative stress and inhibiting the NLRP3 inflammasome
Peritoneal adhesions (PAs) are a serious complication of abdominal surgery and negatively affect the quality of life of millions of people worldwide. However, a clear molecular mechanism and a standard therapeutic strategy for PAs have not been established. Here, we developed a standardized method t...
Autores principales: | Shen, Tianli, Wu, Yunhua, Wang, Xingjie, Wang, Zijun, Li, Enmeng, Zhou, Cancan, Yue, Chenyang, Jiang, Zhengdong, Wei, Guangbing, Lian, Jie, Xu, Qinhong, Li, Xuqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535009/ https://www.ncbi.nlm.nih.gov/pubmed/36100663 http://dx.doi.org/10.1038/s12276-022-00848-3 |
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