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O-GlcNAc transferase regulates intervertebral disc degeneration by targeting FAM134B-mediated ER-phagy

Both O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) and endoplasmic reticulum-phagy (ER-phagy) are well-characterized conserved adaptive regulatory mechanisms that maintain cellular homeostasis and function in response to various stress conditions. Abnormalities in O-GlcNAcylation and ER-pha...

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Detalles Bibliográficos
Autores principales: Luo, Rongjin, Li, Gaocai, Zhang, Weifei, Liang, Huaizhen, Lu, Saideng, Cheung, Jason Pui Yin, Zhang, Teng, Tu, Ji, Liu, Hui, Liao, Zhiwei, Ke, Wencan, Wang, Bingjin, Song, Yu, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535016/
https://www.ncbi.nlm.nih.gov/pubmed/36056188
http://dx.doi.org/10.1038/s12276-022-00844-7