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Assessment of protein inclusions in cultured cells using automated image analysis

Proteinaceous inclusions are associated with neurodegenerative diseases and cell models are often used to determine genetic and chemical modifiers of their formation. This protocol involves the usage of automated microscopy and machine learning-based image analysis to accurately quantify the levels...

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Detalles Bibliográficos
Autores principales: McAlary, Luke, Shephard, Victoria K., Sher, Mine, Rice, Lauren J., Yerbury, Justin J., Cashman, Neil R., Plotkin, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535320/
https://www.ncbi.nlm.nih.gov/pubmed/36201320
http://dx.doi.org/10.1016/j.xpro.2022.101748