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Assessment of protein inclusions in cultured cells using automated image analysis
Proteinaceous inclusions are associated with neurodegenerative diseases and cell models are often used to determine genetic and chemical modifiers of their formation. This protocol involves the usage of automated microscopy and machine learning-based image analysis to accurately quantify the levels...
Autores principales: | McAlary, Luke, Shephard, Victoria K., Sher, Mine, Rice, Lauren J., Yerbury, Justin J., Cashman, Neil R., Plotkin, Steven S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535320/ https://www.ncbi.nlm.nih.gov/pubmed/36201320 http://dx.doi.org/10.1016/j.xpro.2022.101748 |
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