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Serotonin‐deficient neonatal mice are not protected against the development of experimental bronchopulmonary dysplasia or pulmonary hypertension

Serotonin (5‐hydroxytryptamine, 5‐HT) is a potent pulmonary vasoconstrictor and contributes to high pulmonary vascular resistance in the developing ovine lung. In experimental pulmonary hypertension (PH), pulmonary expression of tryptophan hydroxylase‐1 (TPH1), the rate limiting enzyme in 5‐HT synth...

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Detalles Bibliográficos
Autores principales: Roberts, Danielle S., Sherlock, Laura G., Posey, Janelle N., Archambault, Jamie L., Nozik, Eva S., Delaney, Cassidy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535350/
https://www.ncbi.nlm.nih.gov/pubmed/36200294
http://dx.doi.org/10.14814/phy2.15482