Glycerophosphoinositol is Elevated in Blood Samples From CLN3(Δex7-8) pigs, Cln3(Δex7-8) Mice, and CLN3-Affected Individuals

INTRODUCTION: CLN3 Batten disease is a rare pediatric neurodegenerative lysosomal disorder caused by biallelic disease-associated variants in CLN3. Despite decades of intense research, specific biofluid biomarkers of disease status have not been reported, hindering clinical development of therapies....

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Detalles Bibliográficos
Autores principales: Brudvig, Jon J, Swier, Vicki J, Johnson, Tyler B, Cain, Jacob C, Pratt, Melissa, Rechtzigel, Mitch, Leppert, Hannah, Dang Do, An N, Porter, Forbes D, Weimer, Jill M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535353/
https://www.ncbi.nlm.nih.gov/pubmed/36212622
http://dx.doi.org/10.1177/11772719221107765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535353/
https://www.ncbi.nlm.nih.gov/pubmed/36212622
http://dx.doi.org/10.1177/11772719221107765

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