miR-379 mediates insulin resistance and obesity through impaired angiogenesis and adipogenesis regulated by ER stress

We investigated the role of microRNA (miR-379) in the pathogenesis of obesity, adipose tissue dysfunction, and insulin resistance (IR). We used miR-379 knockout (miR-379KO) mice to test whether loss of miR-379 affects high-fat diet (HFD)-induced obesity and IR via dysregulation of key miR-379 target...

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Detalles Bibliográficos
Autores principales: Abdollahi, Maryam, Kato, Mitsuo, Lanting, Linda, Tunduguru, Ragadeepthi, Wang, Mei, Wang, Yangmeng, Fueger, Patrick T., Wang, Qiong, Huang, Wendong, Natarajan, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535382/
https://www.ncbi.nlm.nih.gov/pubmed/36250205
http://dx.doi.org/10.1016/j.omtn.2022.09.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535382/
https://www.ncbi.nlm.nih.gov/pubmed/36250205
http://dx.doi.org/10.1016/j.omtn.2022.09.015

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