Targeted protein degradation in mammalian cells: A promising avenue toward future

In the eukaryotic cellular milieu, proteins are continuously synthesized and degraded effectively via endogenous protein degradation machineries such as the ubiquitin–proteasome and lysosome pathways. By reengineering and repurposing these natural protein regulatory mechanisms, the targeted protein...

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Detalles Bibliográficos
Autores principales: Zhang, Tianyi, Liu, Chuanyang, Li, Wenying, Kuang, Jingyu, Qiu, Xin-yuan, Min, Lu, Zhu, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535385/
https://www.ncbi.nlm.nih.gov/pubmed/36249565
http://dx.doi.org/10.1016/j.csbj.2022.09.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535385/
https://www.ncbi.nlm.nih.gov/pubmed/36249565
http://dx.doi.org/10.1016/j.csbj.2022.09.038

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