Antibody apparent solubility prediction from sequence by transfer learning

Developing therapeutic monoclonal antibodies (mAbs) for the subcutaneous administration requires identifying mAbs with superior solubility that are amenable for high-concentration formulation. However, experimental screening is often material and labor intensive. Here, we present a strategy (named s...

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Detalles Bibliográficos
Autores principales: Feng, Jiangyan, Jiang, Min, Shih, James, Chai, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535432/
https://www.ncbi.nlm.nih.gov/pubmed/36212021
http://dx.doi.org/10.1016/j.isci.2022.105173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535432/
https://www.ncbi.nlm.nih.gov/pubmed/36212021
http://dx.doi.org/10.1016/j.isci.2022.105173

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