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Associations Between Sub-Threshold Amyloid-β Deposition, Cortical Volume, and Cognitive Function Modulated by APOE ɛ4 Carrier Status in Cognitively Normal Older Adults

BACKGROUND: There has been renewed interest in the deteriorating effects of sub-threshold amyloid-β (Aβ) accumulation in Alzheimer’s disease (AD). Despite evidence suggesting a synergistic interaction between the APOE ɛ4 allele and Aβ deposition in neurodegeneration, few studies have investigated th...

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Detalles Bibliográficos
Autores principales: Kang, Dong Woo, Wang, Sheng-Min, Um, Yoo Hyun, Kim, Nak Young, Lee, Chang Uk, Lim, Hyun Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535581/
https://www.ncbi.nlm.nih.gov/pubmed/35964194
http://dx.doi.org/10.3233/JAD-220427