Design, Synthesis, and Study of a Novel RXPA380–Proline Hybrid (RXPA380-P) as an Antihypertensive Agent

[Image: see text] In drug discovery, molecular modification over the lead molecule is often crucial for the development of a drug. Herein, we report the molecular hybridization design of a novel RXPA380–proline hybrid via linking the parent compound, phosphinic peptide RXPA380, with a proline analog...

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Detalles Bibliográficos
Autores principales: Abdou, Moaz M., Dong, Dewen, O’Neill, Paul M., Amigues, Eric, Matziari, Magdalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535653/
https://www.ncbi.nlm.nih.gov/pubmed/36211060
http://dx.doi.org/10.1021/acsomega.2c03813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535653/
https://www.ncbi.nlm.nih.gov/pubmed/36211060
http://dx.doi.org/10.1021/acsomega.2c03813

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