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Process development and preclinical evaluation of a major Plasmodium falciparum blood stage vaccine candidate, Cysteine-Rich Protective Antigen (CyRPA)

Plasmodium falciparum Cysteine-Rich Protective Antigen (CyRPA) is an essential, highly conserved merozoite antigen that forms an important multi-protein complex (RH5/Ripr/CyRPA) necessary for erythrocyte invasion. CyRPA is a promising blood-stage vaccine target that has been shown to elicit potent s...

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Detalles Bibliográficos
Autores principales: Somanathan, Anjali, Mian, Syed Yusuf, Chaddha, Kritika, Uchoi, Seemalata, Bharti, Praveen K., Tandon, Ravi, Gaur, Deepak, Chauhan, Virander Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535676/
https://www.ncbi.nlm.nih.gov/pubmed/36211427
http://dx.doi.org/10.3389/fimmu.2022.1005332