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RAB6 and dynein drive post‐Golgi apical transport to prevent neuronal progenitor delamination

Radial glial (RG) cells are the neural stem cells of the developing neocortex. Apical RG (aRG) cells can delaminate to generate basal RG (bRG) cells, a cell type associated with human brain expansion. Here, we report that aRG delamination is regulated by the post‐Golgi secretory pathway. Using in si...

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Detalles Bibliográficos
Autores principales: Brault, Jean‐Baptiste, Bardin, Sabine, Lampic, Marusa, Carpentieri, Jacopo A, Coquand, Laure, Penisson, Maxime, Lachuer, Hugo, Victoria, Guiliana Soraya, Baloul, Sarah, El Marjou, Fatima, Boncompain, Gaelle, Miserey‐Lenkei, Stephanie, Belvindrah, Richard, Fraisier, Vincent, Francis, Fiona, Perez, Franck, Goud, Bruno, Baffet, Alexandre D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535803/
https://www.ncbi.nlm.nih.gov/pubmed/35979738
http://dx.doi.org/10.15252/embr.202254605