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Bipolar‐associated miR‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2

Bipolar disorder (BD) is a chronic mood disorder characterized by manic and depressive episodes. Dysregulation of neuroplasticity and calcium homeostasis are frequently observed in BD patients, but the underlying molecular mechanisms are largely unknown. Here, we show that miR‐499‐5p regulates dendr...

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Detalles Bibliográficos
Autores principales: Martins, Helena C, Gilardi, Carlotta, Sungur, A Özge, Winterer, Jochen, Pelzl, Michael A, Bicker, Silvia, Gross, Fridolin, Kisko, Theresa M, Malikowska‐Racia, Natalia, Braun, Moria D, Brosch, Katharina, Nenadic, Igor, Stein, Frederike, Meinert, Susanne, Schwarting, Rainer K W, Dannlowski, Udo, Kircher, Tilo, Wöhr, Markus, Schratt, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535808/
https://www.ncbi.nlm.nih.gov/pubmed/35969184
http://dx.doi.org/10.15252/embr.202154420