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T-cells in human trigeminal ganglia express canonical tissue-resident memory T-cell markers

BACKGROUND: Trigeminal ganglia (TG) neurons are the main site of lifelong latent herpes simplex virus type 1 (HSV-1) infection. T-cells in ganglia contribute to long-term control of latent HSV-1 infection, but it is unclear whether these cells are bona fide tissue-resident memory T-cells (T(RM)). We...

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Detalles Bibliográficos
Autores principales: Unger, Peter-Paul A., Oja, Anna E., Khemai-Mehraban, Tamana, Ouwendijk, Werner J. D., Hombrink, Pleun, Verjans, Georges M. G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535861/
https://www.ncbi.nlm.nih.gov/pubmed/36203181
http://dx.doi.org/10.1186/s12974-022-02611-x