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Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus
BACKGROUND: Progesterone receptor (PGR) is a master regulator of uterine function through antagonistic and synergistic interplays with oestrogen receptors. PGR action is primarily mediated by activation functions AF1 and AF2, but their physiological significance is unknown. RESULTS: We report the fi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535881/ https://www.ncbi.nlm.nih.gov/pubmed/36199058 http://dx.doi.org/10.1186/s12915-022-01410-3 |