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Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

BACKGROUND: Progesterone receptor (PGR) is a master regulator of uterine function through antagonistic and synergistic interplays with oestrogen receptors. PGR action is primarily mediated by activation functions AF1 and AF2, but their physiological significance is unknown. RESULTS: We report the fi...

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Detalles Bibliográficos
Autores principales:	Lee, Shi Hao, Lim, Chew Leng, Shen, Wei, Tan, Samuel Ming Xuan, Woo, Amanda Rui En, Yap, Yeannie H. Y., Sian, Caitlyn Ang Su, Goh, Wilson Wen Bin, Yu, Wei-Ping, Li, Li, Lin, Valerie C. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535881/ https://www.ncbi.nlm.nih.gov/pubmed/36199058 http://dx.doi.org/10.1186/s12915-022-01410-3

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