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Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

BACKGROUND: Multiple mutation (MM) within a single gene has recently been reported as a mechanism involved in carcinogenesis. The present study investigated the clinical significance of MMs in hepatocellular carcinoma (HCC). METHODS: Two hundred twenty-three surgically resected HCCs were subjected t...

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Detalles Bibliográficos
Autores principales: Imamura, Taisuke, Okamura, Yukiyasu, Ohshima, Keiichi, Uesaka, Katsuhiko, Sugiura, Teiichi, Ito, Takaaki, Yamamoto, Yusuke, Ashida, Ryo, Ohgi, Katsuhisa, Otsuka, Shimpei, Ohnami, Sumiko, Nagashima, Takeshi, Hatakeyama, Keiichi, Sugino, Takashi, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535898/
https://www.ncbi.nlm.nih.gov/pubmed/36199046
http://dx.doi.org/10.1186/s12885-022-10143-z