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An update on inhibitors targeting RNA-dependent RNA polymerase for COVID-19 treatment: Promises and challenges

The highly transmissible variants of SARS-CoV-2, the causative pathogen of the COVID-19 pandemic, bring new waves of infection worldwide. Identification of effective therapeutic drugs to combat the COVID-19 pandemic is an urgent global need. RNA-dependent RNA polymerase (RdRp), an essential enzyme f...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoying, Chen, Yuheng, Lu, Xinyu, Zhang, Wanlin, Fang, Wenxiu, Yuan, Luping, Wang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535928/
https://www.ncbi.nlm.nih.gov/pubmed/36209840
http://dx.doi.org/10.1016/j.bcp.2022.115279