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Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection

BACKGROUND: Immunosurveillance of the central nervous system (CNS) is vital to resolve infection and injury. However, immune activation within the CNS in the setting of chronic viral infections, such as HIV-1, is strongly linked to progressive neurodegeneration and cognitive decline. Establishment o...

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Detalles Bibliográficos
Autores principales: Hawes, Chase E., Elizaldi, Sonny R., Beckman, Danielle, Diniz, Giovanne B., Shaan Lakshmanappa, Yashavanth, Ott, Sean, Durbin-Johnson, Blythe P., Dinasarapu, Ashok R., Gompers, Andrea, Morrison, John H., Iyer, Smita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535930/
https://www.ncbi.nlm.nih.gov/pubmed/36203187
http://dx.doi.org/10.1186/s12974-022-02610-y