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Identification of Activating Mutations in the Transmembrane and Extracellular Domains of EGFR
[Image: see text] The epidermal growth factor receptor (EGFR) is frequently mutated in human cancer, most notably non-small-cell lung cancer and glioblastoma. While many frequently occurring EGFR mutations are known to confer constitutive EGFR activation, the situation is less clear for rarely detec...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535940/ https://www.ncbi.nlm.nih.gov/pubmed/36148499 http://dx.doi.org/10.1021/acs.biochem.2c00384 |