Identification of Activating Mutations in the Transmembrane and Extracellular Domains of EGFR

[Image: see text] The epidermal growth factor receptor (EGFR) is frequently mutated in human cancer, most notably non-small-cell lung cancer and glioblastoma. While many frequently occurring EGFR mutations are known to confer constitutive EGFR activation, the situation is less clear for rarely detec...

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Detalles Bibliográficos
Autores principales: Wagner, Anja, Galicia-Andrés, Edgar, Teufl, Magdalena, Gold, Lukas, Obinger, Christian, Sykacek, Peter, Oostenbrink, Chris, Traxlmayr, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9535940/
https://www.ncbi.nlm.nih.gov/pubmed/36148499
http://dx.doi.org/10.1021/acs.biochem.2c00384

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