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Nuclear translocation of spike mRNA and protein is a novel pathogenic feature of SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe pathophysiology in vulnerable older populations and appears to be highly pathogenic and more transmissible than SARS-CoV or MERS-CoV [1, 2]. The spike (S) protein appears to be a major pathogenic factor that contributes to th...

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Detalles Bibliográficos
Autores principales: Sattar, Sarah, Kabat, Juraj, Jerome, Kailey, Feldmann, Friederike, Bailey, Kristina, Mehedi, Masfique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536038/
https://www.ncbi.nlm.nih.gov/pubmed/36203551
http://dx.doi.org/10.1101/2022.09.27.509633