Differential modulation of cancer‐related genes by mitochondrial DNA haplogroups and the STING DNA sensing system

Activation of the Simulator of Interferon Genes (STING) system by mitochondrial (mt) DNA can upregulate type 1 interferon genes and enhance immune responses to combat bacterial and viral infections. In cancers, the tumor‐derived DNA activates STING leading to upregulation of IFN‐beta and induction o...

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Detalles Bibliográficos
Autores principales: Schneider, Kevin, Chwa, Marilyn, Atilano, Shari R., Nashine, Sonali, Udar, Nitin, Boyer, David S., Jazwinski, S. Michal, Miceli, Michael V., Nesburn, Anthony B., Kuppermann, Baruch D., Kenney, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536090/
https://www.ncbi.nlm.nih.gov/pubmed/36238361
http://dx.doi.org/10.1096/fba.2019-00044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536090/
https://www.ncbi.nlm.nih.gov/pubmed/36238361
http://dx.doi.org/10.1096/fba.2019-00044

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