Cargando…

Differential modulation of cancer‐related genes by mitochondrial DNA haplogroups and the STING DNA sensing system

Activation of the Simulator of Interferon Genes (STING) system by mitochondrial (mt) DNA can upregulate type 1 interferon genes and enhance immune responses to combat bacterial and viral infections. In cancers, the tumor‐derived DNA activates STING leading to upregulation of IFN‐beta and induction o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schneider, Kevin, Chwa, Marilyn, Atilano, Shari R., Nashine, Sonali, Udar, Nitin, Boyer, David S., Jazwinski, S. Michal, Miceli, Michael V., Nesburn, Anthony B., Kuppermann, Baruch D., Kenney, M. Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536090/ https://www.ncbi.nlm.nih.gov/pubmed/36238361 http://dx.doi.org/10.1096/fba.2019-00044

Ejemplares similares

Human Retinal Transmitochondrial Cybrids with J or H mtDNA Haplogroups Respond Differently to Ultraviolet Radiation: Implications for Retinal Diseases
por: Malik, Deepika, et al.
Publicado: (2014)

Differential effects of cisplatin on cybrid cells with varying mitochondrial DNA haplogroups
por: Abedi, Sina, et al.
Publicado: (2020)

Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular Degeneration
por: Kenney, M. Cristina, et al.
Publicado: (2013)

Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study
por: Kenney, M Cristina, et al.
Publicado: (2013)

Altered Retrograde Signaling Patterns in Breast Cancer Cells Cybrids with H and J Mitochondrial DNA Haplogroups
por: Chang, Steven, et al.
Publicado: (2022)

Low frequency mitochondrial DNA heteroplasmy SNPs in blood, retina, and [RPE+choroid] of age-related macular degeneration subjects
por: Atilano, Shari R., et al.
Publicado: (2021)

Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage
por: Nashine, Sonali, et al.
Publicado: (2017)

PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics
por: Nashine, Sonali, et al.
Publicado: (2019)

Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids
por: Nashine, Sonali, et al.
Publicado: (2016)

Corneal Oxidative Damage in Keratoconus Cells due to Decreased Oxidant Elimination from Modified Expression Levels of SOD Enzymes, PRDX6, SCARA3, CPSF3, and FOXM1
por: Atilano, Shari R., et al.
Publicado: (2019)

European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects
por: Patel, Tej H., et al.
Publicado: (2019)

Role of Resveratrol in Transmitochondrial AMD RPE Cells
por: Nashine, Sonali, et al.
Publicado: (2020)

Potential Therapeutic Functions of PU-91 and Quercetin in Personalized Cybrids Derived from Patients with Age-Related Macular Degeneration, Keratoconus, and Glaucoma
por: Salimiaghdam, Nasim, et al.
Publicado: (2023)

Differential Epigenetic Status and Responses to Stressors between Retinal Cybrids Cells with African versus European Mitochondrial DNA: Insights into Disease Susceptibilities
por: Atilano, Shari R., et al.
Publicado: (2022)

Characterizing the protective effects of SHLP2, a mitochondrial-derived peptide, in macular degeneration
por: Nashine, Sonali, et al.
Publicado: (2018)

Nutraceutical effects of Emblica officinalis in age-related macular degeneration
por: Nashine, Sonali, et al.
Publicado: (2019)

Impacts of Bacteriostatic and Bactericidal Antibiotics on the Mitochondria of the Age-Related Macular Degeneration Cybrid Cell Lines
por: Salimiaghdam, Nasim, et al.
Publicado: (2022)

Anti-VEGF Drugs Influence Epigenetic Regulation and AMD-Specific Molecular Markers in ARPE-19 Cells
por: Hamid, Mohamed A., et al.
Publicado: (2021)

Using Human ‘Personalized’ Cybrids to Identify Drugs/Agents That Can Regulate Chronic Lymphoblastic Leukemia Mitochondrial Dysfunction
por: Singh, Lata, et al.
Publicado: (2023)

Protective Effects of 17β-Estradiol on Benzo(e) pyrene[B(e)P]-induced Toxicity in ARPE-19 cells
por: Sapkal, Ashish U., et al.
Publicado: (2018)

The role of mitochondrial genes on nuclear gene expression in neovascular age related macular degeneration: analysis of nuclear VEGF gene expression after ranibizumab treatment in cytoplasmic hybrid retinal pigment epithelial cell lines correlated with clinical evolution
por: Costa, Rodrigo Donato, et al.
Publicado: (2023)

Hypoxia-induced transcriptional differences in African and Asian versus European diabetic cybrids
por: Dolinko, Andrew H., et al.
Publicado: (2023)

Potential adverse effects of ciprofloxacin and tetracycline on ARPE-19 cell lines
por: Salimiaghdam, Nasim, et al.
Publicado: (2020)

Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells
por: Salimiaghdam, Nasim, et al.
Publicado: (2022)

The Transcriptome Profile of Retinal Pigment Epithelium and Müller Cell Lines Protected by Risuteganib Against Hydrogen Peroxide Stress
por: Shao, Zixuan, et al.
Publicado: (2022)

Autophagy takes the STING out of DNA sensing
por: Maluquer de Motes, Carlos
Publicado: (2021)

Stability Determination of Intact Humanin-G with Characterizations of Oxidation and Dimerization Patterns
por: Ozgul, Mustafa, et al.
Publicado: (2023)

Role of Citicoline in an in vitro AMD model
por: Nashine, Sonali, et al.
Publicado: (2020)

Effects of Mitochondrial-Derived Peptides (MDPs) on Mitochondrial and Cellular Health in AMD
por: Nashine, Sonali, et al.
Publicado: (2020)

Virulent Poxviruses Inhibit DNA Sensing by Preventing STING Activation
por: Georgana, Iliana, et al.
Publicado: (2018)

Mitochondrial DNA haplogroup H structure in North Africa
por: Ennafaa, Hajer, et al.
Publicado: (2009)

Mitochondrial DNA haplogroup distribution in Chaoshanese with and without myopia
por: Wang, Qin, et al.
Publicado: (2010)

Mitochondrial DNA Haplogroup Related to the Prevalence of Helicobacter pylori
por: Lee, Yeonmi, et al.
Publicado: (2021)

Improved Models of Coalescence Ages of Y-DNA Haplogroups
por: McDonald, Iain
Publicado: (2021)

Memantine, Simvastatin, and Epicatechin Inhibit 7-Ketocholesterol-induced Apoptosis in Retinal Pigment Epithelial Cells But Not Neurosensory Retinal Cells In Vitro
por: Neekhra, Aneesh, et al.
Publicado: (2020)

RIGulation of STING expression: at the crossroads of viral RNA and DNA sensing pathways
por: Liu, Yiliu, et al.
Publicado: (2017)

cGAS and STING: At the intersection of DNA and RNA virus-sensing networks
por: Ni, Guoxin, et al.
Publicado: (2018)

The Cytosolic DNA-Sensing cGAS-STING Pathway in Liver Diseases
por: Wang, Zhilei, et al.
Publicado: (2021)

Phylogeography of mtDNA haplogroup R7 in the Indian peninsula
por: Chaubey, Gyaneshwer, et al.
Publicado: (2008)

Origin and spread of human mitochondrial DNA haplogroup U7
por: Sahakyan, Hovhannes, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rsoav5kuifccqsc4ck4nvleeh6