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T-type Ca(2+) channels play a dual role in modulating the excitability of dorsal root ganglia neurons

A subgroup of low-threshold dorsal root ganglia (DRG) neurons discharge action potentials (APs) with an afterdepolarizing potential (ADP). The ADP is formed by T-type Ca(2+) currents. It is known that T-type Ca(2+) currents contribute to neuropathic pain. However, the change in ADP-firing of injured...

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Detalles Bibliográficos
Autores principales: Zhu, Tong, Wang, Yuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536108/
https://www.ncbi.nlm.nih.gov/pubmed/36163701
http://dx.doi.org/10.1177/17448069221132224