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Validation, kinetic modeling, and test-retest reproducibility of [(18)F]SynVesT-1 for PET imaging of synaptic vesicle glycoprotein 2A in mice

Alterations in synaptic vesicle glycoprotein 2 A (SV2A) have been associated with several neuropsychiatric and neurodegenerative disorders. Therefore, SV2A positron emission tomography (PET) imaging may provide a unique tool to investigate synaptic density dynamics during disease progression and aft...

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Detalles Bibliográficos
Autores principales: Bertoglio, Daniele, Zajicek, Franziska, Lombaerde, Stef De, Miranda, Alan, Stroobants, Sigrid, Wang, Yuchuan, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Bard, Jonathan, Liu, Longbin, Verhaeghe, Jeroen, Staelens, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536120/
https://www.ncbi.nlm.nih.gov/pubmed/35570828
http://dx.doi.org/10.1177/0271678X221101648